Ancient Mesoamerican cultures reached extraordinary heights in mathematics, astronomy, architecture, art, farming, and writing. Yet they did not develop the wheel into their means of portage. Constructors most certainly used logs as rollers on which to move huge pieces of sculpture or stones used in construction. The Maya used enormous stone cylinders to flatten their roads. But overland Mesoamerican cargo moved on the backs of porters with tumplines going around their foreheads.
"In Mexico, the wheel was well known, but never applied to transport. It served exclusively for the construction of carriages for toy gods. The taboo on wheelbarrows in America before Cortes is no more puzzling than the taboo on bicycles in modern traffic."